SCREENING & TRIAGE PATHWAYS

Cervical cancer is almost entirely preventable when precancerous lesions are detected and treated early. Yet in low-resource settings, women face long delays, multiple visits, and limited access to accurate diagnostics — leading to late-stage diagnoses and unnecessary deaths.

To address these challenges, we use state-of-the-art screening and triage tools that are proven, scalable, and adapted to low-resource settings:

  • HPV self-sampling

    Women collect their own vaginal sample using a simple swab, often at home or in community settings. This reduces barriers related to distance, privacy, and clinic availability, especially for underserved populations.

  • Biomarker-based triage

    Where suitable we make use of molecular biomarkers (e.g., p16/Ki-67 dual stain) to distinguish transient HPV infections from those likely to progress to precancer or cancer. This improves specificity compared with HPV testing alone, helping to focus colposcopy and treatment on women who truly need it.

  • Advanced colposcopy & visual inspection

    The integration of colposcopy and visual inspection methods (VIA/VILI) with digital tools and decision support standardizes assessment and supports clinicians in making more consistent, evidence-based triage decisions in real time.

Screening process at-a-glance

1. Community Concern

Community talks about health issues including cervical cancer (CC).

4. Laboratory investigation

At laboratory, lab technician performs HPV test on self-sample

2. Community Mobilisation

Community health workers inform about CC program during time limited campaign.

3. Household screening visit

At home visit during screening campaign,  woman self-collects a sample for HPV testing

Health worker carries self-sample registered on e-tablet

5. Delivery of results

Patient gets notified by cellphone about HPV result

6. Walk to clinic

HPV-positive patient has an appointment at the clinic

7. Clinic visit

HPV-positive patient gets examined and, when necessary, treated

8. Screening completed

Patient has successfully completed the screening process

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